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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79003 | HDAC ligand-1 | HDAC | |
HDAC ligand-1 is a synthetic precursor utilized in the production of PROTAC-based HDAC degraders [1]. | |||
T77922 | HDAC6 degrader-1 | PROTACs | |
HDAC6 degrader-1, a proteolysis-targeting chimeric molecule (PROTAC), incorporates the selective HDAC6 inhibitor Nexturastat A (Nex A) for HDAC6 binding, a linker, and an E3 ligase recruiting ligand. This compound effect... | |||
T83947 | HDAC4 CHDI Degrader 11 | ||
HDAC4 CHDI Degrader 11 is a potent, selective degrader of HDAC4 (PROTAC) with DC_50 values of 4 nM and 6 nM in Jurkat E6-1 and Jurkat cells, respectively. This compound integrates the class IIa HDAC inhibitor trifluorome... | |||
T9644 | Triciferol | ||
Triciferol acts as a multiple ligand with combined VDR agonist and HDAC antagonist activities. Triciferol binds directly to the VDR ( IC 50 =87 nM), and functions as an agonist with 1,25D-like potency on several 1,25D ta... |